diff --git a/esp-hal/src/i2c/master/mod.rs b/esp-hal/src/i2c/master/mod.rs
index ebd5bf501..f4797c336 100644
--- a/esp-hal/src/i2c/master/mod.rs
+++ b/esp-hal/src/i2c/master/mod.rs
@@ -3114,7 +3114,7 @@ fn estimate_ack_failed_reason(_register_block: &RegisterBlock) -> AcknowledgeChe
     }
 }
 
-macro_rules! instance {
+crate::peripherals::for_each_i2c_master!(
     ($inst:ident, $peri:ident, $scl:ident, $sda:ident, $interrupt:ident) => {
         impl Instance for crate::peripherals::$inst<'_> {
             fn parts(&self) -> (&Info, &State) {
@@ -3141,12 +3141,7 @@ macro_rules! instance {
             }
         }
     };
-}
-
-#[cfg(i2c_master_i2c0)]
-instance!(I2C0, I2cExt0, I2CEXT0_SCL, I2CEXT0_SDA, I2C_EXT0);
-#[cfg(i2c_master_i2c1)]
-instance!(I2C1, I2cExt1, I2CEXT1_SCL, I2CEXT1_SDA, I2C_EXT1);
+);
 
 crate::any_peripheral! {
     /// Any I2C peripheral.
diff --git a/esp-hal/src/soc/esp32/peripherals.rs b/esp-hal/src/soc/esp32/peripherals.rs
index 5ac75142d..854cc4dd7 100644
--- a/esp-hal/src/soc/esp32/peripherals.rs
+++ b/esp-hal/src/soc/esp32/peripherals.rs
@@ -122,4 +122,5 @@ crate::peripherals! {
     ]
 }
 
+include!(concat!(env!("OUT_DIR"), "/_generated_peris.rs"));
 include!(concat!(env!("OUT_DIR"), "/_generated_gpio.rs"));
diff --git a/esp-hal/src/soc/esp32c2/peripherals.rs b/esp-hal/src/soc/esp32c2/peripherals.rs
index 3297c0266..8509a13eb 100644
--- a/esp-hal/src/soc/esp32c2/peripherals.rs
+++ b/esp-hal/src/soc/esp32c2/peripherals.rs
@@ -82,4 +82,5 @@ crate::peripherals! {
     ]
 }
 
+include!(concat!(env!("OUT_DIR"), "/_generated_peris.rs"));
 include!(concat!(env!("OUT_DIR"), "/_generated_gpio.rs"));
diff --git a/esp-hal/src/soc/esp32c3/peripherals.rs b/esp-hal/src/soc/esp32c3/peripherals.rs
index 0646ff2d5..261a8afe5 100644
--- a/esp-hal/src/soc/esp32c3/peripherals.rs
+++ b/esp-hal/src/soc/esp32c3/peripherals.rs
@@ -100,4 +100,5 @@ crate::peripherals! {
     ]
 }
 
+include!(concat!(env!("OUT_DIR"), "/_generated_peris.rs"));
 include!(concat!(env!("OUT_DIR"), "/_generated_gpio.rs"));
diff --git a/esp-hal/src/soc/esp32c6/peripherals.rs b/esp-hal/src/soc/esp32c6/peripherals.rs
index f3ceaa8f9..3aae03cc5 100644
--- a/esp-hal/src/soc/esp32c6/peripherals.rs
+++ b/esp-hal/src/soc/esp32c6/peripherals.rs
@@ -145,4 +145,5 @@ crate::peripherals! {
     ]
 }
 
+include!(concat!(env!("OUT_DIR"), "/_generated_peris.rs"));
 include!(concat!(env!("OUT_DIR"), "/_generated_gpio.rs"));
diff --git a/esp-hal/src/soc/esp32h2/peripherals.rs b/esp-hal/src/soc/esp32h2/peripherals.rs
index ba285e48f..c9aa606b3 100644
--- a/esp-hal/src/soc/esp32h2/peripherals.rs
+++ b/esp-hal/src/soc/esp32h2/peripherals.rs
@@ -130,4 +130,5 @@ crate::peripherals! {
     ]
 }
 
+include!(concat!(env!("OUT_DIR"), "/_generated_peris.rs"));
 include!(concat!(env!("OUT_DIR"), "/_generated_gpio.rs"));
diff --git a/esp-hal/src/soc/esp32s2/peripherals.rs b/esp-hal/src/soc/esp32s2/peripherals.rs
index 4fece2434..e2ed42fe4 100644
--- a/esp-hal/src/soc/esp32s2/peripherals.rs
+++ b/esp-hal/src/soc/esp32s2/peripherals.rs
@@ -129,4 +129,5 @@ crate::peripherals! {
     ]
 }
 
+include!(concat!(env!("OUT_DIR"), "/_generated_peris.rs"));
 include!(concat!(env!("OUT_DIR"), "/_generated_gpio.rs"));
diff --git a/esp-hal/src/soc/esp32s3/peripherals.rs b/esp-hal/src/soc/esp32s3/peripherals.rs
index cf7a94bd2..0ef7a08cd 100644
--- a/esp-hal/src/soc/esp32s3/peripherals.rs
+++ b/esp-hal/src/soc/esp32s3/peripherals.rs
@@ -138,4 +138,5 @@ crate::peripherals! {
     ]
 }
 
+include!(concat!(env!("OUT_DIR"), "/_generated_peris.rs"));
 include!(concat!(env!("OUT_DIR"), "/_generated_gpio.rs"));
diff --git a/esp-metadata/devices/esp32.toml b/esp-metadata/devices/esp32.toml
index 7164c0900..45aa5aae9 100644
--- a/esp-metadata/devices/esp32.toml
+++ b/esp-metadata/devices/esp32.toml
@@ -551,7 +551,10 @@ output_signals = [
 
 [device.i2c_master]
 support_status = "supported"
-instances = [{ name = "i2c0" }, { name = "i2c1" }]
+instances = [
+    { name = "i2c0", sys_instance = "I2cExt0", scl = "I2CEXT0_SCL", sda = "I2CEXT0_SDA", interrupt = "I2C_EXT0" },
+    { name = "i2c1", sys_instance = "I2cExt1", scl = "I2CEXT1_SCL", sda = "I2CEXT1_SDA", interrupt = "I2C_EXT1" },
+]
 ll_intr_mask = 0x3ffff
 fifo_size = 32
 max_bus_timeout = 0xFFFFF
diff --git a/esp-metadata/devices/esp32c2.toml b/esp-metadata/devices/esp32c2.toml
index b1504eb47..d18ff7a83 100644
--- a/esp-metadata/devices/esp32c2.toml
+++ b/esp-metadata/devices/esp32c2.toml
@@ -195,7 +195,9 @@ output_signals = [
 
 [device.i2c_master]
 support_status = "supported"
-instances = [{ name = "i2c0" }]
+instances = [
+    { name = "i2c0", sys_instance = "I2cExt0", scl = "I2CEXT0_SCL", sda = "I2CEXT0_SDA", interrupt = "I2C_EXT0" },
+]
 has_fsm_timeouts = true
 has_hw_bus_clear = true
 ll_intr_mask = 0x3ffff
diff --git a/esp-metadata/devices/esp32c3.toml b/esp-metadata/devices/esp32c3.toml
index f587e4a49..1a47c90aa 100644
--- a/esp-metadata/devices/esp32c3.toml
+++ b/esp-metadata/devices/esp32c3.toml
@@ -244,7 +244,9 @@ output_signals = [
 
 [device.i2c_master]
 support_status = "supported"
-instances = [{ name = "i2c0" }]
+instances = [
+    { name = "i2c0", sys_instance = "I2cExt0", scl = "I2CEXT0_SCL", sda = "I2CEXT0_SDA", interrupt = "I2C_EXT0" },
+]
 has_fsm_timeouts = true
 has_hw_bus_clear = true
 ll_intr_mask = 0x3ffff
diff --git a/esp-metadata/devices/esp32c6.toml b/esp-metadata/devices/esp32c6.toml
index c22e4ad13..f20a73b99 100644
--- a/esp-metadata/devices/esp32c6.toml
+++ b/esp-metadata/devices/esp32c6.toml
@@ -367,7 +367,9 @@ output_signals = [
 
 [device.i2c_master]
 support_status = "supported"
-instances = [{ name = "i2c0" }]
+instances = [
+    { name = "i2c0", sys_instance = "I2cExt0", scl = "I2CEXT0_SCL", sda = "I2CEXT0_SDA", interrupt = "I2C_EXT0" },
+]
 has_fsm_timeouts = true
 has_hw_bus_clear = true
 ll_intr_mask = 0x3ffff
diff --git a/esp-metadata/devices/esp32h2.toml b/esp-metadata/devices/esp32h2.toml
index b7211cd57..98d93af1d 100644
--- a/esp-metadata/devices/esp32h2.toml
+++ b/esp-metadata/devices/esp32h2.toml
@@ -311,7 +311,10 @@ output_signals = [
 
 [device.i2c_master]
 support_status = "supported"
-instances = [{ name = "i2c0" }, { name = "i2c1" }]
+instances = [
+    { name = "i2c0", sys_instance = "I2cExt0", scl = "I2CEXT0_SCL", sda = "I2CEXT0_SDA", interrupt = "I2C_EXT0" },
+    { name = "i2c1", sys_instance = "I2cExt1", scl = "I2CEXT1_SCL", sda = "I2CEXT1_SDA", interrupt = "I2C_EXT1" },
+]
 has_fsm_timeouts = true
 has_hw_bus_clear = true
 ll_intr_mask = 0x3ffff
diff --git a/esp-metadata/devices/esp32s2.toml b/esp-metadata/devices/esp32s2.toml
index 0bb5eea06..64b100d9b 100644
--- a/esp-metadata/devices/esp32s2.toml
+++ b/esp-metadata/devices/esp32s2.toml
@@ -337,7 +337,10 @@ output_signals = [
 ]
 [device.i2c_master]
 support_status = "supported"
-instances = [{ name = "i2c0" }, { name = "i2c1" }]
+instances = [
+    { name = "i2c0", sys_instance = "I2cExt0", scl = "I2CEXT0_SCL", sda = "I2CEXT0_SDA", interrupt = "I2C_EXT0" },
+    { name = "i2c1", sys_instance = "I2cExt1", scl = "I2CEXT1_SCL", sda = "I2CEXT1_SDA", interrupt = "I2C_EXT1" },
+]
 ll_intr_mask = 0x1ffff
 fifo_size = 32
 has_bus_timeout_enable = true
diff --git a/esp-metadata/devices/esp32s3.toml b/esp-metadata/devices/esp32s3.toml
index b81824c3c..4fdc8b008 100644
--- a/esp-metadata/devices/esp32s3.toml
+++ b/esp-metadata/devices/esp32s3.toml
@@ -485,7 +485,10 @@ output_signals = [
 
 [device.i2c_master]
 support_status = "supported"
-instances = [{ name = "i2c0" }, { name = "i2c1" }]
+instances = [
+    { name = "i2c0", sys_instance = "I2cExt0", scl = "I2CEXT0_SCL", sda = "I2CEXT0_SDA", interrupt = "I2C_EXT0" },
+    { name = "i2c1", sys_instance = "I2cExt1", scl = "I2CEXT1_SCL", sda = "I2CEXT1_SDA", interrupt = "I2C_EXT1" },
+]
 has_fsm_timeouts = true
 has_hw_bus_clear = true
 ll_intr_mask = 0x3ffff
diff --git a/esp-metadata/src/cfg.rs b/esp-metadata/src/cfg.rs
index 59559f059..b712847c1 100644
--- a/esp-metadata/src/cfg.rs
+++ b/esp-metadata/src/cfg.rs
@@ -49,6 +49,14 @@ impl SupportStatus {
 #[derive(Debug, Default, Clone, serde::Deserialize, serde::Serialize)]
 pub(crate) struct EmptyInstanceConfig {}
 
+#[derive(Debug, Default, Clone, serde::Deserialize, serde::Serialize)]
+pub(crate) struct I2cMasterInstanceConfig {
+    pub sys_instance: String,
+    pub scl: String,
+    pub sda: String,
+    pub interrupt: String,
+}
+
 #[derive(Debug, Clone, serde::Deserialize, serde::Serialize)]
 #[serde(rename_all = "snake_case")]
 pub(crate) enum PinCapability {
@@ -349,7 +357,7 @@ driver_configs![
         peripherals: &["hmac"],
         properties: {}
     },
-    I2cMasterProperties {
+    I2cMasterProperties<I2cMasterInstanceConfig> {
         driver: i2c_master,
         name: "I2C master",
         peripherals: &["i2c0", "i2c1"],
diff --git a/esp-metadata/src/lib.rs b/esp-metadata/src/lib.rs
index 88c3d40da..3b4aea0a5 100644
--- a/esp-metadata/src/lib.rs
+++ b/esp-metadata/src/lib.rs
@@ -375,6 +375,7 @@ impl Config {
         self.generate_properties(out_dir, "_generated.rs");
         self.generate_gpios(out_dir, "_generated_gpio.rs");
         self.generate_gpio_extras(out_dir, "_generated_gpio_extras.rs");
+        self.generate_peripherals(out_dir, "_generated_peris.rs");
     }
 
     fn generate_properties(&self, out_dir: &Path, file_name: &str) {
@@ -597,8 +598,8 @@ impl Config {
         let io_mux_accessor = if gpio.remap_iomux_pin_registers {
             let iomux_pin_regs = gpio.pins_and_signals.pins.iter().map(|pin| {
                 let pin = number(pin.pin);
-                let reg = quote::format_ident!("GPIO{pin}");
-                let accessor = quote::format_ident!("gpio{pin}");
+                let reg = format_ident!("GPIO{pin}");
+                let accessor = format_ident!("gpio{pin}");
 
                 quote::quote! { #pin => transmute::<&'static io_mux::#reg, &'static io_mux::GPIO0>(iomux.#accessor()), }
             });
@@ -728,6 +729,43 @@ impl Config {
 
         save(&out_file, g);
     }
+
+    fn generate_peripherals(&self, out_dir: &Path, file_name: &str) {
+        let out_file = out_dir.join(file_name).to_string_lossy().to_string();
+
+        let i2c_master_instance_cfgs = self
+            .device
+            .peri_config
+            .i2c_master
+            .iter()
+            .flat_map(|peri| {
+                peri.instances.iter().map(|instance| {
+                    let instance_config = &instance.instance_config;
+
+                    let instance = format_ident!("{}", instance.name.to_uppercase());
+
+                    let sys = format_ident!("{}", instance_config.sys_instance);
+                    let sda = format_ident!("{}", instance_config.sda);
+                    let scl = format_ident!("{}", instance_config.scl);
+                    let int = format_ident!("{}", instance_config.interrupt);
+
+                    // The order and meaning of these tokens must match their use in the
+                    // `for_each_i2c_master!` call.
+                    quote::quote! {
+                        #instance, #sys, #scl, #sda, #int
+                    }
+                })
+            })
+            .collect::<Vec<_>>();
+
+        let for_each_i2c_master = generate_for_each_macro("i2c_master", &i2c_master_instance_cfgs);
+
+        let g = quote::quote! {
+            #for_each_i2c_master
+        };
+
+        save(&out_file, g);
+    }
 }
 
 fn render_signals(enum_name: &str, signals: &[IoMuxSignal]) -> TokenStream {
@@ -743,7 +781,7 @@ fn render_signals(enum_name: &str, signals: &[IoMuxSignal]) -> TokenStream {
             continue;
         };
 
-        let name = quote::format_ident!("{}", signal.name);
+        let name = format_ident!("{}", signal.name);
         let value = number(id);
         variants.push(quote::quote! {
             #name = #value,
@@ -756,13 +794,13 @@ fn render_signals(enum_name: &str, signals: &[IoMuxSignal]) -> TokenStream {
             continue;
         };
 
-        let name = quote::format_ident!("{}", signal.name);
+        let name = format_ident!("{}", signal.name);
         variants.push(quote::quote! {
             #name,
         });
     }
 
-    let enum_name = quote::format_ident!("{enum_name}");
+    let enum_name = format_ident!("{enum_name}");
 
     quote::quote! {
         #[allow(non_camel_case_types, clippy::upper_case_acronyms)]
@@ -775,6 +813,28 @@ fn render_signals(enum_name: &str, signals: &[IoMuxSignal]) -> TokenStream {
     }
 }
 
+fn generate_for_each_macro(name: &str, branches: &[TokenStream]) -> TokenStream {
+    let macro_name = format_ident!("for_each_{name}");
+    quote::quote! {
+        // This macro is called in esp-hal to implement a driver's
+        // Instance trait for available peripherals. It works by defining, then calling an inner
+        // macro that substitutes the properties into the template provided by the call in esp-hal.
+        macro_rules! #macro_name {
+            (
+                $pattern:tt => $code:tt;
+            ) => {
+                macro_rules! _for_each_inner {
+                    ($pattern) => $code;
+                }
+
+                #(_for_each_inner!(( #branches ));)*
+            };
+        }
+
+        pub(crate) use #macro_name;
+    }
+}
+
 fn save(path: impl AsRef<Path>, tokens: TokenStream) {
     let source = tokens.to_string();