diff --git a/serde_codegen/src/attr.rs b/serde_codegen/src/attr.rs
index b440af7e..1ef63530 100644
--- a/serde_codegen/src/attr.rs
+++ b/serde_codegen/src/attr.rs
@@ -170,6 +170,7 @@ pub struct FieldAttrs {
     skip_serializing_field_if_empty: bool,
     skip_serializing_field_if_none: bool,
     default_expr_if_missing: Option<P<ast::Expr>>,
+    serialize_with: Option<P<ast::Expr>>,
 }
 
 impl FieldAttrs {
@@ -194,6 +195,7 @@ impl FieldAttrs {
             skip_serializing_field_if_empty: false,
             skip_serializing_field_if_none: false,
             default_expr_if_missing: None,
+            serialize_with: None,
         };
 
         for meta_items in field.node.attrs.iter().filter_map(get_serde_meta_items) {
@@ -257,6 +259,18 @@ impl FieldAttrs {
                         field_attrs.skip_serializing_field_if_empty = true;
                     }
 
+                    // Parse `#[serde(serialize_with="...")]`
+                    ast::MetaItemKind::NameValue(ref name, ref lit) if name == &"serialize_with" => {
+                        let expr = wrap_serialize_with(
+                            cx,
+                            container_ty,
+                            generics,
+                            try!(parse_lit_into_expr(cx, name, lit)),
+                        );
+
+                        field_attrs.serialize_with = Some(expr);
+                    }
+
                     _ => {
                         cx.span_err(
                             meta_item.span,
@@ -324,6 +338,10 @@ impl FieldAttrs {
     pub fn skip_serializing_field_if_none(&self) -> bool {
         self.skip_serializing_field_if_none
     }
+
+    pub fn serialize_with(&self) -> Option<&P<ast::Expr>> {
+        self.serialize_with.as_ref()
+    }
 }
 
 
@@ -445,3 +463,55 @@ fn wrap_skip_serializing(cx: &ExtCtxt,
         self.value.__serde_should_skip_serializing()
     })
 }
+
+/// This function wraps the expression in `#[serde(serialize_with="...")]` in a trait to
+/// prevent it from accessing the internal `Serialize` state.
+fn wrap_serialize_with(cx: &ExtCtxt,
+                       container_ty: &P<ast::Ty>,
+                       generics: &ast::Generics,
+                       expr: P<ast::Expr>) -> P<ast::Expr> {
+    let where_clause = &generics.where_clause;
+
+    quote_expr!(cx, {
+        trait __SerdeSerializeWith {
+            fn __serde_serialize_with<S>(&self, serializer: &mut S) -> Result<(), S::Error>
+                where S: ::serde::ser::Serializer;
+        }
+
+        impl<'a, T> __SerdeSerializeWith for &'a T
+            where T: 'a + __SerdeSerializeWith,
+        {
+            fn __serde_serialize_with<S>(&self, serializer: &mut S) -> Result<(), S::Error>
+                where S: ::serde::ser::Serializer
+            {
+                (**self).__serde_serialize_with(serializer)
+            }
+        }
+
+        impl $generics __SerdeSerializeWith for $container_ty $where_clause {
+            fn __serde_serialize_with<S>(&self, serializer: &mut S) -> Result<(), S::Error>
+                where S: ::serde::ser::Serializer
+            {
+                $expr
+            }
+        }
+
+        struct __SerdeSerializeWithStruct<'a, T: 'a> {
+            value: &'a T,
+        }
+
+        impl<'a, T> ::serde::ser::Serialize for __SerdeSerializeWithStruct<'a, T>
+            where T: 'a + __SerdeSerializeWith
+        {
+            fn serialize<S>(&self, serializer: &mut S) -> Result<(), S::Error>
+                where S: ::serde::ser::Serializer
+            {
+                self.value.__serde_serialize_with(serializer)
+            }
+        }
+
+        __SerdeSerializeWithStruct {
+            value: &self.value,
+        }
+    })
+}
diff --git a/serde_codegen/src/ser.rs b/serde_codegen/src/ser.rs
index a604d298..fdf42883 100644
--- a/serde_codegen/src/ser.rs
+++ b/serde_codegen/src/ser.rs
@@ -672,8 +672,13 @@ fn serialize_struct_visitor(
                 }
             };
 
+            let field_expr = match field_attr.serialize_with() {
+                Some(expr) => expr.clone(),
+                None => quote_expr!(cx, &self.value.$name),
+            };
+
             let expr = quote_expr!(cx,
-                serializer.$serializer_method($key_expr, &self.value.$name)
+                serializer.$serializer_method($key_expr, $field_expr)
             );
 
             quote_arm!(cx,
diff --git a/serde_tests/tests/test_annotations.rs b/serde_tests/tests/test_annotations.rs
index 831c32cd..bd640a62 100644
--- a/serde_tests/tests/test_annotations.rs
+++ b/serde_tests/tests/test_annotations.rs
@@ -1,3 +1,6 @@
+use std::default::Default;
+use serde::{Serialize, Serializer};
+
 use token::{
     Error,
     Token,
@@ -11,12 +14,25 @@ trait Trait {
     fn my_default() -> Self;
 
     fn should_skip(&self) -> bool;
+
+    fn serialize_with<S>(&self, ser: &mut S) -> Result<(), S::Error>
+        where S: Serializer;
 }
 
 impl Trait for i32 {
     fn my_default() -> Self { 123 }
 
     fn should_skip(&self) -> bool { *self == 123 }
+
+    fn serialize_with<S>(&self, ser: &mut S) -> Result<(), S::Error>
+        where S: Serializer
+    {
+        if *self == 123 {
+            true.serialize(ser)
+        } else {
+            false.serialize(ser)
+        }
+    }
 }
 
 #[derive(Debug, PartialEq, Serialize, Deserialize)]
@@ -502,3 +518,107 @@ fn test_skip_serializing_enum() {
         ]
     );
 }
+
+#[derive(Debug, PartialEq, Serialize)]
+struct SerializeWithStruct<'a, B> where B: Trait {
+    a: &'a i8,
+    #[serde(serialize_with="self.b.serialize_with(serializer)")]
+    b: B,
+}
+
+#[test]
+fn test_serialize_with_struct() {
+    let a = 1;
+    assert_ser_tokens(
+        &SerializeWithStruct {
+            a: &a,
+            b: 2,
+        },
+        &[
+            Token::StructStart("SerializeWithStruct", Some(2)),
+
+            Token::StructSep,
+            Token::Str("a"),
+            Token::I8(1),
+
+            Token::StructSep,
+            Token::Str("b"),
+            Token::Bool(false),
+
+            Token::StructEnd,
+        ]
+    );
+
+    assert_ser_tokens(
+        &SerializeWithStruct {
+            a: &a,
+            b: 123,
+        },
+        &[
+            Token::StructStart("SerializeWithStruct", Some(2)),
+
+            Token::StructSep,
+            Token::Str("a"),
+            Token::I8(1),
+
+            Token::StructSep,
+            Token::Str("b"),
+            Token::Bool(true),
+
+            Token::StructEnd,
+        ]
+    );
+}
+
+#[derive(Debug, PartialEq, Serialize)]
+enum SerializeWithEnum<'a, B> where B: Trait {
+    Struct {
+        a: &'a i8,
+        #[serde(serialize_with="self.b.serialize_with(serializer)")]
+        b: B,
+    }
+}
+
+#[test]
+fn test_serialize_with_enum() {
+    let a = 1;
+    assert_ser_tokens(
+        &SerializeWithEnum::Struct {
+            a: &a,
+            b: 2,
+        },
+        &[
+            Token::EnumMapStart("SerializeWithEnum", "Struct", Some(2)),
+
+            Token::EnumMapSep,
+            Token::Str("a"),
+            Token::I8(1),
+
+            Token::EnumMapSep,
+            Token::Str("b"),
+            Token::Bool(false),
+
+            Token::EnumMapEnd,
+        ]
+    );
+
+    assert_ser_tokens(
+        &SerializeWithEnum::Struct {
+            a: &a,
+            b: 123,
+        },
+        &[
+            Token::EnumMapStart("SerializeWithEnum", "Struct", Some(2)),
+
+            Token::EnumMapSep,
+            Token::Str("a"),
+            Token::I8(1),
+
+            Token::EnumMapSep,
+            Token::Str("b"),
+            Token::Bool(true),
+
+            Token::EnumMapEnd,
+        ]
+    );
+}