diff --git a/README.md b/README.md
index 830efafb5..8e4fa0564 100644
--- a/README.md
+++ b/README.md
@@ -56,7 +56,7 @@ Make sure you activated the full features of the tokio crate on Cargo.toml:
 
 ```toml
 [dependencies]
-tokio = { version = "1.45.0", features = ["full"] }
+tokio = { version = "1.45.1", features = ["full"] }
 ```
 Then, on your main.rs:
 
diff --git a/tokio/CHANGELOG.md b/tokio/CHANGELOG.md
index 2d2f94ba0..27f84c867 100644
--- a/tokio/CHANGELOG.md
+++ b/tokio/CHANGELOG.md
@@ -1,3 +1,15 @@
+# 1.45.1 (May 24th, 2025)
+
+This fixes a regression on the wasm32-unknown-unknown target, where code that
+previously did not panic due to calls to `Instant::now()` started failing. This
+is due to the stabilization of the first time-based metric.
+
+### Fixed
+
+- Disable time-based metrics on wasm32-unknown-unknown ([#7322])
+
+[#7322]: https://github.com/tokio-rs/tokio/pull/7322
+
 # 1.45.0 (May 5th, 2025)
 
 ### Added
diff --git a/tokio/Cargo.toml b/tokio/Cargo.toml
index fd7223445..e4be60d0e 100644
--- a/tokio/Cargo.toml
+++ b/tokio/Cargo.toml
@@ -6,7 +6,7 @@ name = "tokio"
 #   - README.md
 # - Update CHANGELOG.md.
 # - Create "v1.x.y" git tag.
-version = "1.45.0"
+version = "1.45.1"
 edition = "2021"
 rust-version = "1.70"
 authors = ["Tokio Contributors <team@tokio.rs>"]
diff --git a/tokio/README.md b/tokio/README.md
index 830efafb5..8e4fa0564 100644
--- a/tokio/README.md
+++ b/tokio/README.md
@@ -56,7 +56,7 @@ Make sure you activated the full features of the tokio crate on Cargo.toml:
 
 ```toml
 [dependencies]
-tokio = { version = "1.45.0", features = ["full"] }
+tokio = { version = "1.45.1", features = ["full"] }
 ```
 Then, on your main.rs:
 
diff --git a/tokio/src/runtime/metrics/batch.rs b/tokio/src/runtime/metrics/batch.rs
index 00f9c9898..fe2f4a9da 100644
--- a/tokio/src/runtime/metrics/batch.rs
+++ b/tokio/src/runtime/metrics/batch.rs
@@ -12,7 +12,7 @@ pub(crate) struct MetricsBatch {
     busy_duration_total: u64,
 
     /// Instant at which work last resumed (continued after park).
-    processing_scheduled_tasks_started_at: Instant,
+    processing_scheduled_tasks_started_at: Option<Instant>,
 
     /// Number of times the worker parked.
     park_count: u64,
@@ -67,17 +67,17 @@ cfg_unstable_metrics! {
 
 impl MetricsBatch {
     pub(crate) fn new(worker_metrics: &WorkerMetrics) -> MetricsBatch {
-        let now = Instant::now();
-        Self::new_unstable(worker_metrics, now)
+        let maybe_now = now();
+        Self::new_unstable(worker_metrics, maybe_now)
     }
 
     cfg_metrics_variant! {
         stable: {
             #[inline(always)]
-            fn new_unstable(_worker_metrics: &WorkerMetrics, now: Instant) -> MetricsBatch {
+            fn new_unstable(_worker_metrics: &WorkerMetrics, maybe_now: Option<Instant>) -> MetricsBatch {
                 MetricsBatch {
                     busy_duration_total: 0,
-                    processing_scheduled_tasks_started_at: now,
+                    processing_scheduled_tasks_started_at: maybe_now,
                     park_count: 0,
                     park_unpark_count: 0,
                 }
@@ -85,7 +85,16 @@ impl MetricsBatch {
         },
         unstable: {
             #[inline(always)]
-            fn new_unstable(worker_metrics: &WorkerMetrics, now: Instant) -> MetricsBatch {
+            fn new_unstable(worker_metrics: &WorkerMetrics, maybe_now: Option<Instant>) -> MetricsBatch {
+                let poll_timer = maybe_now.and_then(|now| {
+                    worker_metrics
+                        .poll_count_histogram
+                        .as_ref()
+                        .map(|worker_poll_counts| PollTimer {
+                            poll_counts: HistogramBatch::from_histogram(worker_poll_counts),
+                            poll_started_at: now,
+                        })
+                });
                 MetricsBatch {
                     park_count: 0,
                     park_unpark_count: 0,
@@ -97,13 +106,8 @@ impl MetricsBatch {
                     local_schedule_count: 0,
                     overflow_count: 0,
                     busy_duration_total: 0,
-                    processing_scheduled_tasks_started_at: now,
-                    poll_timer: worker_metrics.poll_count_histogram.as_ref().map(
-                        |worker_poll_counts| PollTimer {
-                            poll_counts: HistogramBatch::from_histogram(worker_poll_counts),
-                            poll_started_at: now,
-                        },
-                    ),
+                    processing_scheduled_tasks_started_at: maybe_now,
+                    poll_timer,
                 }
             }
         }
@@ -186,13 +190,17 @@ impl MetricsBatch {
 
     /// Start processing a batch of tasks
     pub(crate) fn start_processing_scheduled_tasks(&mut self) {
-        self.processing_scheduled_tasks_started_at = Instant::now();
+        self.processing_scheduled_tasks_started_at = now();
     }
 
     /// Stop processing a batch of tasks
     pub(crate) fn end_processing_scheduled_tasks(&mut self) {
-        let busy_duration = self.processing_scheduled_tasks_started_at.elapsed();
-        self.busy_duration_total += duration_as_u64(busy_duration);
+        if let Some(processing_scheduled_tasks_started_at) =
+            self.processing_scheduled_tasks_started_at
+        {
+            let busy_duration = processing_scheduled_tasks_started_at.elapsed();
+            self.busy_duration_total += duration_as_u64(busy_duration);
+        }
     }
 
     cfg_metrics_variant! {
@@ -279,3 +287,17 @@ cfg_rt_multi_thread! {
 pub(crate) fn duration_as_u64(dur: Duration) -> u64 {
     u64::try_from(dur.as_nanos()).unwrap_or(u64::MAX)
 }
+
+/// Gate unsupported time metrics for `wasm32-unknown-unknown`
+/// <https://github.com/tokio-rs/tokio/issues/7319>
+fn now() -> Option<Instant> {
+    if cfg!(all(
+        target_arch = "wasm32",
+        target_os = "unknown",
+        target_vendor = "unknown"
+    )) {
+        None
+    } else {
+        Some(Instant::now())
+    }
+}